Cardiac troponin T in unstable angina

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Troponin T in the evaluation of prognosis in patients with unstable angina

441 Abstract: Cardiac troponin T (TnT) is a regulatory contractile protein not normally found in blood. Minor elevations of TnT in patients with unstable angina have been associated with an increased risk of subsequent death or Acute Myocardial Infarction (AMI). We used a neewly developed enzyme immunoassay for TnT to determine whether its presence in the serum of patients with unstable angina ...

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Increased concentrations of inflammatory mediators in unstable angina: correlation with serum troponin T.

OBJECTIVE To measure plasma interferon gamma, monocyte chemotactic protein-1 (MCP-1), and interleukin 6 and to assess their correlation with cardiac troponin T in unstable angina. DESIGN Blood sampling in patients undergoing coronary arteriography for known or suspected ischaemic heart disease. PATIENTS 76 patients divided in three groups: 29 with unstable angina (group 1), 28 with stable a...

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Angiographic findings in patients with refractory unstable angina according to troponin T status.

BACKGROUND The CAPTURE (C7E3 fab AntiPlatelet Therapy in Unstable REfactory angina) trial enrolled patients with refractory unstable angina and documented a therapeutic benefit for abciximab, a platelet glycoprotein IIb/IIIa receptor antagonist, that was particularly evident in patients with elevated troponin T (TnT) levels. In the current study, we related the angiographic data to the TnT stat...

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Prognostic role of troponin T versus troponin I in unstable angina pectoris for cardiac events with meta-analysis comparing published studies.

Controversy exists as to the clinical roles and relative specificities of cardiac troponin T or I in patients with unstable angina pectoris (UAP). We measured troponin T and I levels on admission in 123 patients with UAP. Of the 107 patients with normal creatine kinase during the first 24 hours, troponin T and I were elevated in 14 and 13 patients, respectively. At 30 days, 5 of 14 patients (36...

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NMR-based plasma metabolic profiling in patients with unstable angina

Objective(s): Unstable angina (UA) is a form of the acute coronary syndrome (ACS) that affects more than a third of the population before age 70. Due to the limitations of diagnostic tests, appropriate identification of UA is difficult. In this study, we proceeded to investigate metabolite profiling in UA patients compared with controls to determine potential candidate...

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ژورنال

عنوان ژورنال: BMJ

سال: 1996

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.313.7068.1330a